The ability of different genetic variants—changes to one or more building blocks of DNA—to cause disease, and to what extent, ...

New spatial transcriptomics approach combined with machine learning maps gene expression across whole mouse body sections, ...

Sometimes, a small error in the sequence of DNA can lead to a very serious disease. Scientists have identified many mutations that arise in a single gene to cause an ...

The Human Genome Project changed everything. A map of the entire human sequence of DNA was the starting point for an enormous number of discoveries, from disease genes to how humans evolved. But DNA ...

The genetics of autism has long been one of the most intricate puzzles in neurodevelopmental science. Today, the pieces are coming together more rapidly than ever before. Landmark projects such as the ...

The pathology of mental disorders is complex. Researchers can’t just attribute mental disorders to one or a few single mutations in a gene or protein — there are too many factors at play. After all, ...

Cross-species research shows that RNA splicing patterns, not just gene activity, track maximum lifespan in mammals, revealing ...

The contribution of genetics to the variability in people’s metabolism has remained largely unknown. This is, in part, because genetic studies of human metabolism have been limited in scale and ...

In A Nutshell A large genetic study found significant overlap between certain psychiatric conditions and 73 physical diseases ...